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Foscarnet Sodium

Chemical name: Phosphonoformic acid, trisodium salt, hexahydrate
Molecular formula: CNa3O5P·6H2O
Molecular weight: 300.04
CAS: 34156-56-4
Structural formula:

Specification:
A: In accordance with Chinese national standard WS1(X-187)-2004Z
Characters: White crystalline powder. Odorless.
Alkalinity: 9.5~10.5
Solution clarity and color: The solution should be clear and colorless.
Phosphate: ≤0.45%
Phosphite: ≤0.38%
Loss on drying: 35.0~37.0%
Assay: Not less than 99.0% of CNa3O5P·6H2O on the dried basis.
Heavy metal: ≤10ppm
Total aerobic microbial count: Not more than 103cfu/g.
Total yeast and mold count: Not more than 102cfu/g.
B: In accordance with USP
Appearance: White or off-white crystalline powder.
pH: 9.0~11.0
Loss on drying: 35.0~37.0%
Heavy Metal: ≤10ppm
Assay (calculated on dried basis): 98.5~101.0%
Impurity B: ≤0.15%
Any individual unspecified impurity: ≤0.05%
Total impurities: ≤0.4%
Phosphate: ≤0.3%
Phosphite: ≤0.3%
Impurity D: ≤0.1%
Bacterial endotoxins: ≤0.0833EU/mg
Total aerobic microbial count: ≤100cfu/g
Total yeast and mold count: ≤50cfu/g

Packing size: 25Kg/drum
Authentication code: Guo Yao Zhun Zi H20083179
Indications: Anti-viral drugs. In vitro inhibition of herpesvirus DNA polymerases, including cytomegalovirus, HSV-1, HSV-2, HHV-6, EBV and VZV.

 
 
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